Description

6-Amino-2-Thia-Spiro[3.3]Heptane is a specialized spirocyclic building block featuring a unique fused ring system containing both amine and thioether functionalities. This compound matters as a high-value intermediate for constructing complex molecular architectures in advanced pharmaceutical and agrochemical research. It is primarily needed by medicinal chemists and process development scientists for applications in drug discovery, particularly in the synthesis of novel bioactive molecules targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides with novel modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands and organocatalysts due to its constrained spirocyclic geometry.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tool compounds for studying enzyme function and biological pathways.

Basic Information

Product Name	6-Amino-2-Thia-Spiro[3.3]Heptane
CAS No.	1363381-30-9
Molecular Formula	C6H11NS
Molecular Weight	129.22 g/mol
Synonyms	6-Amino-2-thiaspiro[3.3]heptane; 2-Thia-6-azaspiro[3.3]heptane; 6-Amino-2-thiaspiro(3.3)heptane; 6-Amino-2-thia-spiro[3.3]heptane; Spiro[3.3]heptane-6-amine, 2-thia-; 2-Thia-6-azaspiro[3.3]heptane; 1363381-30-9; 6-Amino-2-thia-spiro(3.3)heptane
EINECS	Contact for details

Quality Control

Our 6-Amino-2-Thia-Spiro[3.3]Heptane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.