Description

2-(Phenylsulfonyl)-6-Oxo-2-Azaspiro[3.3]Heptane is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic and sulfonamide scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting complex diseases. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in protease inhibitor and kinase inhibitor research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained spirocyclic geometry.
• Chemical Biology Probes: Serves as a core structure for developing enzyme inhibitors and molecular probes to study biological pathways.
• Agrochemical Development: Potential intermediate in the research and synthesis of new generation herbicides and fungicides.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory synthetic chemistry and method development.
• Custom Synthesis: Foundation for the custom manufacturing of specialized fine chemicals and bespoke intermediates for client-specific projects.

Basic Information

Product Name	2-(Phenylsulfonyl)-6-Oxo-2-Azaspiro[3.3]Heptane
CAS No.	1363381-24-1
Molecular Formula	C12H13NO3S
Molecular Weight	251.30 g/mol
Synonyms	6-Oxo-2-(phenylsulfonyl)-2-azaspiro[3.3]heptane; 2-Azaspiro[3.3]heptane-6-one, 2-(phenylsulfonyl)-; 2-(Benzenesulfonyl)-6-oxo-2-azaspiro[3.3]heptane; 2-Phenylsulfonyl-6-oxo-2-azaspiro[3.3]heptane; 2-(Phenylsulfonyl)-6-oxo-2-azaspiro[3.3]heptane; 1363381-24-1; 2-(Phenylsulfonyl)-6-oxo-2-azaspiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our 2-(Phenylsulfonyl)-6-Oxo-2-Azaspiro[3.3]Heptane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.