Description

tert-Butyl 7-Oxo-2-Azaspiro[3.5]Nonane-2-Carboxylate is a high-value, protected spirocyclic lactam building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research, serving as a versatile scaffold for constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Scaffold: Used as a constrained, spirocyclic core for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Protease Inhibitor Development: Serves as a building block for the synthesis of inhibitors targeting various protease enzymes.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic Research: Employed in university and institutional labs for methodological development in synthetic organic chemistry and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 7-Oxo-2-Azaspiro[3.5]Nonane-2-Carboxylate
CAS No.	1363381-22-9
Molecular Formula	C13H21NO3
Molecular Weight	239.31 g/mol
Synonyms	2-Azaspiro[3.5]nonane-2-carboxylic acid, 7-oxo-, 1,1-dimethylethyl ester; tert-Butyl 7-oxo-2-azaspiro[3.5]nonane-2-carboxylate; 7-Oxo-2-azaspiro[3.5]nonane-2-carboxylic acid tert-butyl ester; 2-Boc-7-oxo-2-azaspiro[3.5]nonane; Boc-7-oxo-2-azaspiro[3.5]nonane; 2-(tert-Butoxycarbonyl)-7-oxo-2-azaspiro[3.5]nonane
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Oxo-2-Azaspiro[3.5]Nonane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.