Description

2-[(tert-Butoxy)Carbonyl]-2-Azaspiro[4.5]Decane-7-Carboxylic Acid is a high-value, protected amino acid derivative featuring a spirocyclic structure. This compound serves as a critical advanced pharmaceutical intermediate (API) for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities (NCEs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Peptidomimetics Research: Used to introduce constrained, spirocyclic motifs into peptide backbones to enhance metabolic stability and binding affinity.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by providing a versatile scaffold for further functionalization.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	2-[(tert-Butoxy)Carbonyl]-2-Azaspiro[4.5]Decane-7-Carboxylic Acid
CAS No.	1363381-11-6
Molecular Formula	C15H25NO4
Molecular Weight	283.36 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)]-2-azaspiro[4.5]decane-7-carboxylic acid; 2-(Boc)-2-azaspiro[4.5]decane-7-carboxylic acid; 2-Azaspiro[4.5]decane-7-carboxylic acid, 2-[(1,1-dimethylethoxy)carbonyl]-; Boc-2-azaspiro[4.5]decane-7-carboxylic acid; 7-Carboxy-2-azaspiro[4.5]decane-2-carboxylic acid tert-butyl ester; 1363381-11-6; tert-Butyl 7-carboxy-2-azaspiro[4.5]decane-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 2-[(tert-Butoxy)Carbonyl]-2-Azaspiro[4.5]Decane-7-Carboxylic Acid adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.