Description

7-Boc-10-Oxo-2,7-Diaza-Spiro[4.5]Decane is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing spirocyclic and bridged heterocyclic compounds in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Used in the synthesis of linker components and warhead conjugates for targeted protein degradation therapies.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	7-Boc-10-Oxo-2,7-Diaza-Spiro[4.5]Decane
CAS No.	1363380-92-0
Molecular Formula	C13H22N2O3
Molecular Weight	254.33 g/mol
Synonyms	tert-Butyl 10-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate; 2,7-Diaza-spiro[4.5]decane-7-carboxylic acid, 10-oxo-, 1,1-dimethylethyl ester; 7-(tert-Butoxycarbonyl)-10-oxo-2,7-diazaspiro[4.5]decane; 7-Boc-2,7-diaza-spiro[4.5]decan-10-one; Boc-protected diazaspirodecanone
EINECS	Contact for details

Quality Control

Our 7-Boc-10-Oxo-2,7-Diaza-Spiro[4.5]Decane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.