Description

Ethyl 3-Chloro-5-Nitropyridine-4-Acetate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive nitro and chloro substituents, which enable precise derivatization for creating complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Material Science Research: Serves as a building block for creating functionalized ligands, coordination complexes, and specialty polymers.
• Chemical Research & Development: Employed in academic and industrial labs for method development, cross-coupling reactions, and heterocyclic chemistry studies.
• Fine Chemical Production: Acts as a critical intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	Ethyl 3-Chloro-5-Nitropyridine-4-Acetate
CAS No.	1363380-74-8
Molecular Formula	C9H9ClN2O4
Molecular Weight	244.63 g/mol
Synonyms	Ethyl (3-chloro-5-nitropyridin-4-yl)acetate; 4-Pyridineacetic acid, 3-chloro-5-nitro-, ethyl ester; 3-Chloro-5-nitroisonicotinic acid ethyl ester; Ethyl 3-chloro-5-nitroisonicotinate; (3-Chloro-5-nitropyridin-4-yl)acetic acid ethyl ester; 1363380-74-8; Ethyl 3-chloro-5-nitro-4-pyridylacetate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Chloro-5-Nitropyridine-4-Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.