Description

cis-4-Aminotetrahydropyran-3-Ol is a high-purity, advanced pharmaceutical intermediate featuring a unique fused heterocyclic structure. This compound is valued for its role as a critical chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapies.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex target molecules for clinical trials and commercial production.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology & Proteomics: Employed as a specialty reagent for modifying peptides or creating molecular probes to study biological pathways.
• Catalyst & Ligand Development: Acts as a precursor for synthesizing novel chiral catalysts and ligands used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom chemical production projects.

Basic Information

Product Name	cis-4-Aminotetrahydropyran-3-Ol
CAS No.	1363380-59-9
Molecular Formula	C5H11NO2
Molecular Weight	117.15 g/mol
Synonyms	4-Amino-3-hydroxytetrahydropyran (cis-); (3R,4S)-4-Aminotetrahydro-2H-pyran-3-ol; (3S,4R)-4-Aminotetrahydro-2H-pyran-3-ol; cis-4-Amino-3-hydroxytetrahydropyran; 3-Pyranol, 4-amino-tetrahydro-, cis-; 4-Aminotetrahydropyran-3-ol; Tetrahydropyran-3-ol, 4-amino-
EINECS	Contact for details

Quality Control

Our cis-4-Aminotetrahydropyran-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.