Description

2-Chloro-3-Fluoro-5-(Trifluoromethoxy)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring chlorine, fluorine, and a trifluoromethoxy substituent, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials that require specific halogenated aromatic systems.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex pyridine motifs into target molecules.

Basic Information

Product Name	2-Chloro-3-Fluoro-5-(Trifluoromethoxy)Pyridine
CAS No.	1361841-92-0
Molecular Formula	C7H2ClF4NO
Molecular Weight	215.54 g/mol
Synonyms	2-Chloro-3-fluoro-5-(trifluoromethoxy)pyridine; 5-(Trifluoromethoxy)-2-chloro-3-fluoropyridine; Pyridine, 2-chloro-3-fluoro-5-(trifluoromethoxy)-; 1361841-92-0; 2-Chloro-3-fluoro-5-trifluoromethoxypyridine
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for our advanced intermediates. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC/GC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.