Description

Pyridine, 2-(Chloromethyl)-6-(Trifluoromethoxy)- is a specialized halogenated pyridine derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both chloromethyl and trifluoromethoxy substituents, makes it a critical building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries, where it is instrumental in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethoxy group.
• Ligand and Catalyst Development: Serves as a precursor for creating novel pyridine-based ligands used in transition metal catalysis and material science.
• Functional Material Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Pyridine, 2-(Chloromethyl)-6-(Trifluoromethoxy)-
CAS No.	1361692-49-0
Molecular Formula	C8H7ClF3NO
Molecular Weight	225.60 g/mol
Synonyms	2-(Chloromethyl)-6-(trifluoromethoxy)pyridine; 6-(Trifluoromethoxy)-2-pyridinemethanol, chloride; 2-Chloromethyl-6-trifluoromethoxypyridine; (6-(Trifluoromethoxy)pyridin-2-yl)methyl chloride; 2-Pyridinemethanol, 6-(trifluoromethoxy)-, chloride
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 2-(Chloromethyl)-6-(Trifluoromethoxy)- is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider maintaining the material under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.