Description

2-(5-Bromo-Pyridin-2-Yl)-Morpholine-4-Carboxylic Acid tert-Butyl Ester is a high-value, multi-functional chemical building block designed for advanced synthesis. This compound is critical for research and development in pharmaceutical chemistry, serving as a key intermediate in the creation of novel active pharmaceutical ingredients (APIs). It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients in crop protection products.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects at gram to kilogram scale.

Basic Information

Product Name	2-(5-Bromo-Pyridin-2-Yl)-Morpholine-4-Carboxylic Acid tert-Butyl Ester
CAS No.	1361112-38-0
Molecular Formula	C14H19BrN2O3
Molecular Weight	343.22 g/mol
Synonyms	tert-Butyl 2-(5-bromopyridin-2-yl)morpholine-4-carboxylate; 4-(tert-Butoxycarbonyl)-2-(5-bromo-2-pyridinyl)morpholine; 2-(5-Bromo-2-pyridinyl)-4-[(1,1-dimethylethoxy)carbonyl]morpholine; 1361112-38-0; Morpholine-4-carboxylic acid, 2-(5-bromo-2-pyridinyl)-, 1,1-dimethylethyl ester; Boc-2-(5-Bromo-pyridin-2-yl)-morpholine
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-Pyridin-2-Yl)-Morpholine-4-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support cGMP and ISO standards for pharmaceutical intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.