Description

Azetidine-3-Carboxylic Acid Amide Trifluoroacetic Acid Salt is a high-purity, protected heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key precursor in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting protease enzymes and neurological pathways. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, drug discovery, and the synthesis of complex peptidomimetics.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, especially protease inhibitors and central nervous system (CNS) active compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Peptidomimetic Synthesis: Serves as a constrained, azetidine-based scaffold to mimic peptide structures and enhance metabolic stability.
• Chemical Biology Probes: Employed in the development of tool compounds and probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring high-purity, specialized heterocycles.

Basic Information

Product Name	Azetidine-3-Carboxylic Acid Amide Trifluoroacetic Acid Salt
CAS No.	1361111-58-1
Molecular Formula	C6H9F3N2O3
Molecular Weight	214.15 g/mol
Synonyms	3-Amidinoazetidine Trifluoroacetate; Azetidine-3-carboxamide, Trifluoroacetic acid salt; 3-Carbamoylazetidine Trifluoroacetate; 1-Azetidine-3-carboxylic acid amide TFA salt; (Azetidin-3-yl)carboxamide trifluoroacetate; 3-Azetidinecarboxamide, trifluoroacetic acid salt
EINECS	Contact for details

Quality Control

Our Azetidine-3-Carboxylic Acid Amide Trifluoroacetic Acid Salt is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation upon exposure to air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.