Description

5'-Methoxy-1'H-Spiro[Cyclopropane-1,3'-Indole]-2'-One is a high-value, complex spirocyclic indole derivative used as a key synthetic intermediate in advanced organic chemistry. This compound matters for its unique structural framework, which is integral to the development of novel bioactive molecules and pharmaceuticals. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of new chemical entities targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those with spirocyclic or indole-based scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new pharmacophores.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the production of active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Acts as a precursor for developing tool compounds and probes to study biological pathways and protein functions.
• Agrochemical Research: Investigated as an intermediate for creating new crop protection agents with novel modes of action.
• Academic Research: Utilized in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5'-Methoxy-1'H-Spiro[Cyclopropane-1,3'-Indole]-2'-One
CAS No.	1360946-96-8
Molecular Formula	C12H11NO2
Molecular Weight	201.22 g/mol
Synonyms	5'-Methoxy-1'H-spiro[cyclopropane-1,3'-indol]-2'(2'H)-one; 5'-Methoxy-1'H-spiro[cyclopropane-1,3'-indole]-2'-one; 1'H-Spiro[cyclopropane-1,3'-indole]-2'-one, 5'-methoxy-; Spiro[cyclopropane-1,3'-indole]-2'-one, 5'-methoxy-; 1360946-96-8; 5-Methoxyspiro[cyclopropane-1,3'-indolin]-2'-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for each parameter are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.