Description

Dimethyl 3-(Trifluoromethyl)Pyridine-2,5-Dicarboxylate is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both ester and trifluoromethyl groups, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by material scientists exploring specialty polymers and electronic chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional materials due to its electron-deficient aromatic core.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Dimethyl 3-(Trifluoromethyl)Pyridine-2,5-Dicarboxylate
CAS No.	1360944-09-7
Molecular Formula	C10H8F3NO4
Molecular Weight	263.17 g/mol
Synonyms	2,5-Pyridinedicarboxylic acid, 3-(trifluoromethyl)-, dimethyl ester; Dimethyl 3-(trifluoromethyl)pyridine-2,5-dicarboxylate; 3-(Trifluoromethyl)pyridine-2,5-dicarboxylic acid dimethyl ester; Methyl 3-(trifluoromethyl)pyridine-2,5-dicarboxylate; 2,5-Dimethoxycarbonyl-3-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of Dimethyl 3-(Trifluoromethyl)Pyridine-2,5-Dicarboxylate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and we support customer audits and regulatory documentation as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.