Description

Methyl 2-Chloro-5-(Trifluoromethyl)Nicotinate is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound is valued for its role as a key building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the biological activity of the nicotinate and trifluoromethyl motifs.
• Chemical Research & Development: Serves as a versatile scaffold for organic synthesis, enabling the exploration of new chemical spaces in academic and industrial R&D labs.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for metal-catalyzed reactions or as a component in material science applications.

Basic Information

Product Name	Methyl 2-Chloro-5-(Trifluoromethyl)Nicotinate
CAS No.	1360934-51-5
Molecular Formula	C8H5ClF3NO2
Molecular Weight	239.58 g/mol
Synonyms	Methyl 2-chloro-5-(trifluoromethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-chloro-5-(trifluoromethyl)-, methyl ester; 2-Chloro-5-trifluoromethylnicotinic acid methyl ester; Methyl 2-chloro-5-trifluoromethylnicotinate; 1360934-51-5; Methyl 2-chloro-5-(trifluoromethyl)-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-5-(Trifluoromethyl)Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.