Description

(E)-Ethyl 3-(4-Morpholinophenyl)Acrylate is a high-purity, synthetic organic building block characterized by its conjugated acrylate ester structure linked to a morpholine-substituted phenyl ring. This compound matters as a versatile and critical intermediate for advanced pharmaceutical research and fine chemical synthesis, enabling the construction of complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and kinase inhibition.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or precursor for functional polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Utilized in Heck-type coupling reactions, Michael additions, and other C-C bond-forming transformations to create complex molecular architectures.
• Academic & Institutional R&D: Employed in universities and research institutes for methodological studies and exploring new chemical spaces.
• Custom Synthesis & Contract Manufacturing: A starting material for the production of bespoke compounds and APIs under cGMP or research-grade conditions.

Basic Information

Product Name	(E)-Ethyl 3-(4-Morpholinophenyl)Acrylate
CAS No.	1359868-31-7
Molecular Formula	C15H19NO3
Molecular Weight	261.32 g/mol
Synonyms	Ethyl (E)-3-(4-Morpholinophenyl)acrylate; (E)-Ethyl 3-(4-Morpholinyl)phenylacrylate; 2-Propenoic acid, 3-(4-morpholinylphenyl)-, ethyl ester, (E)-; 4-[3-(Ethoxycarbonyl)-2-propen-1-yl]morpholine; Ethyl (E)-3-(4-Morpholin-4-ylphenyl)prop-2-enoate; NSC 781102; AKOS005258065
EINECS	Contact for details

Quality Control

Our (E)-Ethyl 3-(4-Morpholinophenyl)Acrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and GC for residual solvent analysis, to ensure it meets exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (E/Z ratio by HPLC)	≥ 98:2 (E:Z)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.