Description

Benzyl 2-Oxo-6-Azaspiro[3.5]Nonane-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for constructing complex molecular architectures, particularly in the development of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of new chemical entities (NCEs) for drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Key Intermediate in Drug Discovery: Serves as a critical building block for synthesizing potential drug candidates with spirocyclic motifs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new pharmacophores and improve drug-like properties.
• Protease Inhibitor Development: The 2-oxo (lactam) and spirocyclic structure makes it relevant for designing inhibitors of specific enzymes.
• CNS-Active Compound Synthesis: Applied in the research and development of novel agents for neurological and psychiatric conditions.
• Chemical Biology Probes: Utilized to create specialized molecules for studying biological pathways and target engagement.
• Custom Synthesis & Scale-Up: Supplied for process research and development (PR&D) and non-GMP pilot-scale manufacturing.

Basic Information

Product Name	Benzyl 2-Oxo-6-Azaspiro[3.5]Nonane-6-Carboxylate
CAS No.	1359705-27-3
Molecular Formula	C16H19NO3
Molecular Weight	273.33 g/mol
Synonyms	6-(Benzyloxycarbonyl)-2-oxo-6-azaspiro[3.5]nonane; Benzyl 2-oxo-6-azaspiro[3.5]nonane-6-carboxylate; 6-CBZ-2-Oxo-6-azaspiro[3.5]nonane; 2-Oxo-6-azaspiro[3.5]nonane-6-carboxylic acid benzyl ester; 6-[(Benzyloxy)carbonyl]-2-oxo-6-azaspiro[3.5]nonane; 6-Azaspiro[3.5]nonane-6-carboxylic acid, 2-oxo-, benzyl ester; Spirocyclic Lactam CBZ Ester
EINECS	Contact for details

Quality Control

Our Benzyl 2-Oxo-6-Azaspiro[3.5]Nonane-6-Carboxylate is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for research and development applications. Each batch is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.