Description

4-(tert-Butyldimethylsilyloxy)-N1-Propylbenzene-1,2-Diamine is a specialized aromatic diamine derivative featuring a tert-butyldimethylsilyl (TBDMS) protecting group. This compound matters as a high-value pharmaceutical intermediate and organic synthesis building block, prized for its role in constructing complex molecules where selective amine protection is required. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its diamine functionality.
• Organic Synthesis Reagent: Serves as a protected diamine precursor in multi-step synthetic routes, including peptide mimetics and heterocyclic compound formation.
• Ligand and Catalyst Development: Potential precursor for creating chelating ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Can be incorporated into polymer backbones to introduce reactive amine sites for further functionalization or cross-linking.
• Research & Development: Essential for academic and industrial research exploring new chemical reactions and material properties.

Basic Information

Product Name	4-(tert-Butyldimethylsilyloxy)-N1-Propylbenzene-1,2-Diamine
CAS No.	1359701-99-7
Molecular Formula	C15H28N2OSi
Molecular Weight	280.49 g/mol
Synonyms	1,2-Benzenediamine, 4-[(1,1-dimethylethyl)dimethylsilyl]oxy]-N1-propyl-; 4-(TBDMS-oxy)-N1-propyl-1,2-benzenediamine; 4-[(tert-Butyldimethylsilyl)oxy]-N-propylbenzene-1,2-diamine; N1-Propyl-4-(tert-butyldimethylsilyloxy)benzene-1,2-diamine; TBDMS-protected propylbenzenediamine; 4-(tert-Butyldimethylsilyloxy)-N-propyl-o-phenylenediamine
EINECS	Contact for details

Quality Control

Our 4-(tert-Butyldimethylsilyloxy)-N1-Propylbenzene-1,2-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.