Description

Imidazo[1,2-A]Pyridine-3-Carboxylic Acid, 6-(Trifluoromethyl)-, Ethyl Ester is a high-value, multi-functional heterocyclic building block characterized by its fused imidazopyridine core and trifluoromethyl group. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where it imparts favorable physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting CNS disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functional additive in the creation of specialty polymers and organic electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a fluorescent tag or ligand in biochemical assays.
• Academic & Contract Research: Essential for synthetic methodology development and exploration of new heterocyclic chemistry in university and CRO laboratories.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine-3-Carboxylic Acid, 6-(Trifluoromethyl)-, Ethyl Ester
CAS No.	1359657-11-6
Molecular Formula	C11H9F3N2O2
Molecular Weight	258.20 g/mol
Synonyms	Ethyl 6-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate; 6-(Trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-3-carboxylic acid, 6-(trifluoromethyl)-, ethyl ester; CAS 1359657-11-6; 6-CF3-Imidazo[1,2-a]pyridine-3-ethyl carboxylate
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-A]Pyridine-3-Carboxylic Acid, 6-(Trifluoromethyl)-, Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with each shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.