Description

6-Oxa-2-Azaspiro[3.5]Nonane Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in developing new therapeutics, especially in areas like neurology and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its spirocyclic structure.
• API Development: Serves as a core scaffold for constructing novel active pharmaceutical ingredients with potential improved efficacy and selectivity.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological targets and mechanisms of action.
• Custom Synthesis: Employed by fine chemical manufacturers for bespoke synthesis projects requiring specialized heterocyclic frameworks.

Basic Information

Product Name	6-Oxa-2-Azaspiro[3.5]Nonane Hydrochloride
CAS No.	1359656-29-3
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	6-Oxa-2-azaspiro[3.5]nonane hydrochloride; 2-Aza-6-oxaspiro[3.5]nonane hydrochloride; 6-Oxa-2-azaspiro[3.5]nonane HCl; Spiro[3.5]nonane-6-one, 2-aza-, hydrochloride; 1-Oxa-5-azaspiro[2.5]octane hydrochloride (alternative numbering); 1359656-29-3; 6-Oxa-2-azaspiro[3.5]nonane monohydrochloride
EINECS	Contact for details

Quality Control

Our 6-Oxa-2-Azaspiro[3.5]Nonane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.