Description

tert-Butyl 2,6-diazaspiro[3.4]octane-2-carboxylate is a high-value, nitrogen-containing spirocyclic building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research, serving as a versatile scaffold for constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Scaffold: Utilized as a privileged spirocyclic structure to explore novel chemical space and improve the pharmacokinetic properties of lead molecules.
• Proteolysis Targeting Chimera (PROTAC) Development: Incorporated as a linker or core component in the design of bifunctional degraders.
• Chemical Biology Probes: Serves as a building block for creating tool compounds to study biological pathways and protein function.
• Agrochemical Research: Used in the discovery and development of new active ingredients with enhanced efficacy.
• Academic & Contract Research: Employed in universities and CROs for method development and exploring new synthetic routes involving spirocyclic amines.

Basic Information

Product Name	tert-Butyl 2,6-diazaspiro[3.4]octane-2-carboxylate
CAS No.	1359656-10-2
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	2,6-Diazaspiro[3.4]octane-2-carboxylic acid, 1,1-dimethylethyl ester; 2-(tert-Butoxycarbonyl)-2,6-diazaspiro[3.4]octane; Boc-2,6-diazaspiro[3.4]octane; tert-Butyl 2,6-diaza-spiro[3.4]octane-2-carboxylate; 2,6-Diazaspiro[3.4]octane-2-carboxylic acid tert-butyl ester; 2-Boc-2,6-diazaspiro[3.4]octane; 1359656-10-2
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,6-diazaspiro[3.4]octane-2-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.