Description

6-Oxa-1-Azaspiro[3.3]Heptane Oxalate is a high-purity, advanced pharmaceutical intermediate and building block of significant interest in modern organic synthesis. Its unique spirocyclic structure makes it a valuable scaffold for medicinal chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Scaffold: Used to construct spirocyclic cores in drug discovery programs, leveraging its three-dimensional structure to explore new chemical space.
• Agrochemical Synthesis: Serves as a precursor in the development of new generation herbicides and fungicides with novel modes of action.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and R&D: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and corporate R&D centers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	6-Oxa-1-Azaspiro[3.3]Heptane Oxalate
CAS No.	1359655-43-8
Molecular Formula	C8H11NO5
Molecular Weight	201.18 g/mol
Synonyms	6-Oxa-1-azaspiro[3.3]heptane oxalate; 1-Oxa-4-azaspiro[2.3]hexane oxalate (alternative numbering); Oxaspiroheptane oxalate salt; 6-Oxa-1-azaspiro[3.3]heptane, oxalic acid salt; Azaspiro[3.3]heptane oxalate derivative; Spirocyclic oxazolidine oxalate; Building block 1359655-43-8
EINECS	Contact for details

Quality Control

Every batch of 6-Oxa-1-Azaspiro[3.3]Heptane Oxalate is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.