Description

Spiro[Cyclohexane-1,3'-[3H]Indol]-2'(1'H)-One, 1'-(4-Piperidinyl)- is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic indole-piperidine structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily required by research and development organizations in the pharmaceutical and biotechnology sectors for drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly those with spirocyclic architectures.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• CNS-Active Compound Synthesis: Serves as a core scaffold for molecules targeting neurological receptors and pathways.
• Chemical Biology Probe Development: Utilized to create tool compounds for studying specific biological mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API (Active Pharmaceutical Ingredient) development projects.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis methodology and novel heterocycle chemistry.

Basic Information

Product Name	Spiro[Cyclohexane-1,3'-[3H]Indol]-2'(1'H)-One, 1'-(4-Piperidinyl)-
CAS No.	1358667-64-7
Molecular Formula	C18H22N2O
Molecular Weight	282.38 g/mol
Synonyms	1'-(4-Piperidinyl)spiro[cyclohexane-1,3'-[3H]indol]-2'(1'H)-one; 1'-(Piperidin-4-yl)-1'H-spiro[cyclohexane-1,3'-indol]-2'-one; 1'-(4-Piperidyl)spiro[cyclohexane-1,3'-indol]-2'-one; Spiro[cyclohexane-1,3'-indole]-2'-one, 1'-(4-piperidinyl)-; 1358667-64-7; CAS 1358667-64-7
EINECS	Contact for details

Quality Control

Our Spiro[Cyclohexane-1,3'-[3H]Indol]-2'(1'H)-One, 1'-(4-Piperidinyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), residual solvents, and other critical parameters is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.