Description

1-Piperidinecarboxylic Acid, 4-(2'-Oxospiro[Cyclopropane-1,3'-[3H]Indol]-1'(2'H)-Yl)-, 1,1-Dimethylethyl Ester is a sophisticated, high-purity organic building block featuring a complex spirocyclic indole-piperidine hybrid structure. This compound is of significant value in advanced pharmaceutical research and development, serving as a critical intermediate for synthesizing novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and library synthesis to explore new bioactive molecules.
• Process Chemistry Development: Serves as a starting material or advanced intermediate for scaling up synthetic routes under GMP conditions.
• Proteolysis Targeting Chimera (PROTAC) Development: Its structural features make it a potential component for designing linker or ligand elements in targeted protein degradation platforms.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying enzyme function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific research programs.

Basic Information

Item	Details
Product Name	1-Piperidinecarboxylic Acid, 4-(2'-Oxospiro[Cyclopropane-1,3'-[3H]Indol]-1'(2'H)-Yl)-, 1,1-Dimethylethyl Ester
CAS No.	1358667-55-6
Molecular Formula	C20H24N2O3
Molecular Weight	340.42 g/mol
Synonyms	tert-Butyl 4-(2'-oxospiro[cyclopropane-1,3'-indol]-1'(2'H)-yl)piperidine-1-carboxylate; 1-Boc-4-(2'-oxospiro[cyclopropane-1,3'-indolin]-1'-yl)piperidine; 1-(1-Boc-4-piperidinyl)-2'-oxospiro[cyclopropane-1,3'-indoline]; Spiro[cyclopropane-1,3'-indol]-2'-one, 1'-[1-(1,1-dimethylethoxycarbonyl)-4-piperidinyl]-; BOC-Spiroindolone-piperidine; CAS 1358667-55-6
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 4-(2'-Oxospiro[Cyclopropane-1,3'-[3H]Indol]-1'(2'H)-Yl)-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for demanding research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.