Description

2-Chloro-1-(4-Chloropyridin-2-Yl)Ethanone is a high-purity, specialized organic building block featuring a reactive α-chloroketone moiety adjacent to a dichloropyridine ring. This compound matters as a critical synthetic intermediate, enabling the construction of complex heterocyclic scaffolds essential for advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel heterocyclic compounds with potential biological activity.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its reactive halogen sites.
• Chemical Synthesis: Serves as a versatile electrophile in nucleophilic substitution and cross-coupling reactions.
• Material Science Precursor: Potential starting material for creating functionalized ligands or organic electronic materials.
• Academic & Contract Research: Valuable reagent for methodological studies and library synthesis in medicinal chemistry.

Basic Information

Product Name	2-Chloro-1-(4-Chloropyridin-2-Yl)Ethanone
CAS No.	1357946-32-7
Molecular Formula	C7H5Cl2NO
Molecular Weight	190.03 g/mol
Synonyms	2-Chloro-1-(4-chloro-2-pyridinyl)ethanone; 1-(4-Chloro-2-pyridinyl)-2-chloroethanone; 2-Chloro-1-(4-chloropyridin-2-yl)ethan-1-one; 4-Chloro-2-pyridyl chloromethyl ketone; Ethanone, 2-chloro-1-(4-chloro-2-pyridinyl)-; 1357946-32-7; 2,4-Dichloro-pyridinyl methyl ketone
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(4-Chloropyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.