Description

n-(4-Methyl-5-(2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)Pyridin-4-Yl)Thiazol-2-Yl)-1H-Imidazole-1-Carboxamide CAS NO 1357476-70-0 is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure containing thiazole, pyridine, and imidazole moieties. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the research and synthesis of new drug candidates, especially in oncology and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, leveraging its complex heterocyclic scaffold for biological activity.
• Chemical Biology Probe: Employed in academic and industrial research as a molecular tool to study enzyme inhibition and protein-ligand interactions.
• Material Science: Investigated as a potential monomer or additive for creating specialty polymers with unique electronic or optical properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	n-(4-Methyl-5-(2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)Pyridin-4-Yl)Thiazol-2-Yl)-1H-Imidazole-1-Carboxamide
CAS No.	1357476-70-0
Molecular Formula	C17H15F3N6OS
Molecular Weight	408.40 g/mol
Synonyms	1H-Imidazole-1-carboxamide, N-[4-methyl-5-[2-(1,1,1-trifluoro-2-methyl-2-propanyl)-4-pyridinyl]-2-thiazolyl]-; 1357476-70-0; UNII-1F3T9G8Q3U; 1F3T9G8Q3U; CHEMBL3186662; BDBM50157871; AKOS025147324; n-(4-Methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)-1H-imidazole-1-carboxamide
EINECS	Contact for details

Quality Control

Our production of n-(4-Methyl-5-(2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)Pyridin-4-Yl)Thiazol-2-Yl)-1H-Imidazole-1-Carboxamide adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements, supporting development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.