Description

2-Thiazolamine, 4-Methyl-5-[2-(2,2,2-Trifluoro-1,1-Dimethylethyl)-4-Pyridinyl]- is a high-value, structurally complex heterocyclic compound featuring a thiazole core linked to a substituted pyridine ring. This molecule matters for its role as a sophisticated pharmaceutical intermediate and key building block in advanced organic synthesis. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with enhanced efficacy.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and materials science applications.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Advanced Material Development: A potential monomer or additive in the creation of specialty polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	2-Thiazolamine, 4-Methyl-5-[2-(2,2,2-Trifluoro-1,1-Dimethylethyl)-4-Pyridinyl]-
CAS No.	1357476-69-7
Molecular Formula	C14H14F3N3S
Molecular Weight	313.34 g/mol
Synonyms	4-Methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)pyridin-4-yl]-1,3-thiazol-2-amine; 4-Methyl-5-(2-(2,2,2-trifluoro-1,1-dimethylethyl)pyridin-4-yl)thiazol-2-amine; 2-Amino-4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]thiazole; 4-Methyl-5-(2-(2,2,2-trifluoro-tert-butyl)pyridin-4-yl)thiazol-2-amine; CAS 1357476-69-7
EINECS	Contact for details

Quality Control

Our production of 2-Thiazolamine, 4-Methyl-5-[2-(2,2,2-Trifluoro-1,1-Dimethylethyl)-4-Pyridinyl]- adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for advanced intermediates and can tailor quality documentation to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.