Description

Methyl 2-(Cyclopropylethynyl)Benzoate is a specialized benzoate ester derivative featuring a cyclopropylethynyl substituent, serving as a high-value synthetic intermediate in advanced organic chemistry. This compound is critical for research and development, enabling the construction of complex molecular architectures with precise spatial control. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring constrained three-dimensional structures.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the cyclopropylethynyl moiety can contribute to unique biological activity.
• Material Science Research: Employed in the development of advanced organic electronic materials, liquid crystals, or polymers where its rigid, conjugated structure can modulate electronic properties.
• Academic & Contract Research: Serves as a valuable reagent in university and CRO (Contract Research Organization) laboratories for methodology development and exploring new chemical spaces.
• Ligand & Catalyst Development: Acts as a precursor for creating specialized ligands or organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	Methyl 2-(Cyclopropylethynyl)Benzoate
CAS No.	1357469-11-4
Molecular Formula	C13H12O2
Molecular Weight	200.23 g/mol
Synonyms	2-(Cyclopropylethynyl)benzoic acid methyl ester; Methyl o-(cyclopropylethynyl)benzoate; Benzoic acid, 2-(2-cyclopropylethynyl)-, methyl ester; Methyl 2-(2-cyclopropylethynyl)benzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-(Cyclopropylethynyl)Benzoate is produced and analyzed under strict quality management protocols to ensure consistency and purity for critical R&D and scale-up processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are available upon request to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC / GC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.