Description

2-Isobutoxypyridine-3-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative crucial for modern synthetic chemistry. This compound serves as a key building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel pyridine-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific pyridine-based architectures.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs) due to its functional handle.
• Chemical Biology & Probe Development: Acts as a versatile building block for creating molecular probes and bioconjugates used in diagnostic and biochemical research.
• Process Chemistry & Scale-up: Supplied for route scouting, optimization, and pilot-scale production under cGMP guidelines where applicable.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories worldwide.

Basic Information

Product Name	2-Isobutoxypyridine-3-Boronic Acid Pinacol Ester
CAS No.	1357397-80-8
Molecular Formula	C15H24BNO3
Molecular Weight	277.17 g/mol
Synonyms	2-(Isobutoxy)pyridine-3-boronic acid pinacol ester; 3-Pyridineboronic acid, 2-(2-methylpropoxy)-, 1,1-dimethylethyl ester; 2-Isobutoxy-3-pyridinylboronic acid pinacol ester; 2-(2-Methylpropoxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Boronic acid, B-[2-(2-methylpropoxy)-3-pyridinyl]-, 1,1-dimethylethyl ester; 1357397-80-8; 2-Isobutoxy-3-pyridineboronic acid pinacol ester.
EINECS	Contact for details

Quality Control

Our 2-Isobutoxypyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.