Description

2,7-Diaza-Spiro[4.4]Nonane-2,9-Dicarboxylic Acid 2-tert-Butyl Ester 9-Ethyl Ester is a high-value, multifunctional spirocyclic building block essential for advanced organic synthesis. This compound matters as a key chiral intermediate and scaffold in the development of novel pharmaceuticals and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research and development teams in pharmaceutical, biotechnology, and agrochemical industries for drug discovery, process chemistry, and the synthesis of active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used as a key chiral scaffold in the research and development of new generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe Synthesis: Employed in the construction of molecular probes and tool compounds for studying biological pathways and target validation.
• Peptidomimetics and Macrocycle Synthesis: The spirocyclic and diaza structure is valuable for designing constrained peptides and macrocyclic compounds with improved metabolic stability and binding affinity.
• Material Science Research: Potential use as a monomer or building block for developing novel polymers and functional materials with specific chemical properties.

Basic Information

Product Name	2,7-Diaza-Spiro[4.4]Nonane-2,9-Dicarboxylic Acid 2-tert-Butyl Ester 9-Ethyl Ester
CAS No.	1357354-49-4
Molecular Formula	C16H28N2O4
Molecular Weight	312.41 g/mol
Synonyms	2,7-Diaza-spiro[4.4]nonane-2,9-dicarboxylic acid, 2-(1,1-dimethylethyl) 9-ethyl ester; 2-tert-Butyl 9-ethyl 2,7-diazaspiro[4.4]nonane-2,9-dicarboxylate; 2,7-Diazaspiro[4.4]nonane-2,9-dicarboxylic Acid 2-tert-Butyl Ester 9-Ethyl Ester; Ethyl 2-(tert-butoxycarbonyl)-2,7-diazaspiro[4.4]nonane-9-carboxylate; 9-Ethyl 2-tert-butyl 2,7-diazaspiro[4.4]nonane-2,9-dicarboxylate; BOC-Diazaspiro[4.4]nonane-ethyl ester; Diazaspiro[4.4]nonane diester derivative
EINECS	Contact for details

Quality Control

Our 2,7-Diaza-Spiro[4.4]Nonane-2,9-Dicarboxylic Acid 2-tert-Butyl Ester 9-Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and consideration given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.