Description

2-(tert-Butoxycarbonyl)-7-Oxo-2,6-Diazaspiro[3.4]Octane-5-Carboxylic Acid (Wx100918) is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and diaza scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for constructing novel drug candidates. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutics, particularly in areas like protease inhibitors and other small molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting enzymatic pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) around complex heterocyclic cores.
• Protease Inhibitor Development: The spirocyclic diaza structure is highly relevant for designing potent inhibitors of various protease enzymes.
• Custom Synthesis: Serves as a starting material or advanced intermediate for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery programs.
• Chemical Biology Probes: Useful for creating specialized molecular tools to study biological processes and protein function.

Basic Information

Item	Details
Product Name	2-(tert-Butoxycarbonyl)-7-Oxo-2,6-Diazaspiro[3.4]Octane-5-Carboxylic Acid (Wx100918)
CAS No.	1357351-94-0
Molecular Formula	C13H18N2O5
Molecular Weight	282.29 g/mol
Synonyms	Boc-7-Oxo-2,6-diazaspiro[3.4]octane-5-carboxylic acid; 2,6-Diazaspiro[3.4]octane-5-carboxylic acid, 2-[(1,1-dimethylethoxy)carbonyl]-7-oxo-; 2-(Boc)-7-oxo-2,6-diazaspiro[3.4]octane-5-carboxylic acid; tert-Butyl 5-carboxy-7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate; Wx100918; 1357351-94-0; 2,6-Diazaspiro[3.4]octane-5-carboxylic acid, 2-[(tert-butoxy)carbonyl]-7-oxo-
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxycarbonyl)-7-Oxo-2,6-Diazaspiro[3.4]Octane-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.