Description

1,3,2-Dioxaborolane, 2,2'-[2,5-Bis(Bromomethyl)-1,4-Phenylene]Bis[4,4,5,5-Tetramethyl- is a high-value, multi-functional organoboron building block designed for advanced synthetic chemistry. This compound is critical for constructing complex molecular architectures due to its dual reactive sites—bromomethyl groups and protected boronic ester functionalities. It is primarily sought after by research and development teams in the pharmaceutical and advanced materials sectors for creating novel active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in drug candidates.
• Polymer Chemistry: Serves as a difunctional monomer or cross-linking agent for creating specialty polymers, such as boron-containing polyesters or networks for electronic materials.
• Ligand Synthesis: Precursor for synthesizing sophisticated chelating ligands used in catalysis and material science.
• Organic Electronics: Used in the development of organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs) due to its ability to incorporate boron into π-conjugated systems.
• Chemical Biology Probes: Enables the tagging and modification of biomolecules for research and diagnostic applications.
• Advanced Material Research: Fundamental component in covalent organic frameworks (COFs) and other porous materials research.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2,2'-[2,5-Bis(Bromomethyl)-1,4-Phenylene]Bis[4,4,5,5-Tetramethyl-
CAS No.	1356822-77-9
Molecular Formula	C22H32B2Br2O4
Molecular Weight	558.01 g/mol
Synonyms	2,5-Bis(bromomethyl)-1,4-phenylenebis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); 1,4-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-bis(bromomethyl)benzene; 2,5-Bis(bromomethyl)-1,4-phenylenebis(pinacol boronate); 2,5-Bis(bromomethyl)-1,4-phenylenebis(pinacolato diboron); 2,5-Bis(bromomethyl)-1,4-phenylene bis(boronic acid pinacol ester); 2,5-Bis(bromomethyl)benzene-1,4-diboronic acid bis(pinacol) ester; 2,5-Dibromomethyl-1,4-phenylenebis(pinacol boronate); (2,5-Bis(bromomethyl)-1,4-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)
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Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.