Description

2-(sec-Butoxy)-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, organoboron-protected pyridine derivative, serving as a critical advanced pharmaceutical intermediate and building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex pyridine cores.
• Suzuki-Miyaura Cross-Coupling: The protected boronic ester group makes it an ideal reagent for palladium-catalyzed carbon-carbon bond formation, a cornerstone of modern medicinal chemistry.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers, where its molecular structure can be incorporated into larger conjugated systems.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	2-(sec-Butoxy)-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1356699-45-0
Molecular Formula	C16H26BNO3
Molecular Weight	291.20 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(sec-butoxy)-4-methylpyridine; 2-(sec-Butoxy)-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Methyl-2-(sec-butoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol ester of [2-(sec-butoxy)-4-methylpyridin-5-yl]boronic acid; 5-Boronic acid, 2-(1-methylpropoxy)-4-methylpyridine, pinacol ester; Pyridine, 2-(1-methylpropoxy)-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; B-Protected Pyridine Boronic Ester
EINECS	Contact for details

Quality Control

Our 2-(sec-Butoxy)-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.