Description

Methyl 2-Oxo-1,3-Dihydropyrrolo[3,2-B]Pyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is essential for research and development chemists and process scale-up teams in the pharmaceutical and biotechnology industries seeking to develop new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing fused pyrrolopyridine scaffolds, which are privileged structures in drug discovery.
• Research & Development: Serves as a standard or starting material in academic and industrial R&D for exploring new chemical entities and biological activities.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of potential APIs under cGMP conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Methyl 2-Oxo-1,3-Dihydropyrrolo[3,2-B]Pyridine-3-Carboxylate
CAS No.	1356542-85-2
Molecular Formula	C10H8N2O3
Molecular Weight	204.18 g/mol
Synonyms	Methyl 2-oxo-1,3-dihydro-2H-pyrrolo[3,2-b]pyridine-3-carboxylate; 3-Carbomethoxy-2-oxo-1,2-dihydropyrrolo[3,2-b]pyridine; 1,3-Dihydro-2-oxopyrrolo[3,2-b]pyridine-3-carboxylic Acid Methyl Ester; Methyl 1,3-dihydro-2-oxopyrrolo[3,2-b]pyridine-3-carboxylate; 2H-Pyrrolo[3,2-b]pyridine-3-carboxylic acid, 1,3-dihydro-2-oxo-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Oxo-1,3-Dihydropyrrolo[3,2-B]Pyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The material may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.