Description

tert-Butyl 2-Methylidene-7-Azaspiro[3.5]Nonane-7-Carboxylate is a specialized spirocyclic building block of significant interest in advanced organic synthesis. This compound serves as a key intermediate for constructing complex nitrogen-containing heterocycles, which are core scaffolds in modern pharmaceutical discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel spirocyclic drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action, leveraging its unique spirocyclic structure.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Serves as a versatile linker or core component in the design of bifunctional molecules for targeted protein degradation.
• Material Science: Potential monomer or precursor for creating polymers with specific thermal or mechanical properties due to its rigid, three-dimensional geometry.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in spiroannulation and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 2-Methylidene-7-Azaspiro[3.5]Nonane-7-Carboxylate
CAS No.	1356476-38-4
Molecular Formula	C14H23NO2
Molecular Weight	237.34 g/mol
Synonyms	7-Boc-2-Methylidene-7-azaspiro[3.5]nonane; tert-Butyl 2-methylidene-7-azaspiro[3.5]nonane-7-carboxylate; 2-Methylidene-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester; 7-(tert-Butoxycarbonyl)-2-methylidene-7-azaspiro[3.5]nonane; 2-Methylene-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester; Boc-2-Methylidene-7-azaspiro[3.5]nonane; 1356476-38-4
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Methylidene-7-Azaspiro[3.5]Nonane-7-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.