Description

1H-Benzimidazole, 2-(6-Fluoro-3-Pyridinyl)-6-(Trifluoromethyl)- is a high-value, fluorinated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both benzimidazole and fluoropyridine motifs, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily targeted at R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate sophisticated fluorine-containing scaffolds into their molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop next-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the benzimidazole core and the metabolic stability imparted by fluorine.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging agent in the design of chemical probes and enzyme inhibitors for biological research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	1H-Benzimidazole, 2-(6-Fluoro-3-Pyridinyl)-6-(Trifluoromethyl)-
CAS No.	1356385-98-2
Molecular Formula	C13H7F4N3
Molecular Weight	281.21 g/mol
Synonyms	2-(6-Fluoropyridin-3-yl)-6-(trifluoromethyl)-1H-benzimidazole; 6-Fluoro-3-(6-(trifluoromethyl)-1H-benzimidazol-2-yl)pyridine; 1356385-98-2; 2-(6-Fluoro-3-pyridinyl)-6-(trifluoromethyl)-1H-benzimidazole; 6-(Trifluoromethyl)-2-(6-fluoro-3-pyridinyl)-1H-benzimidazole; 2-(6-Fluoropyridin-3-yl)-6-trifluoromethyl-1H-benzimidazole; 1H-Benzimidazole, 2-(6-fluoro-3-pyridinyl)-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 1H-Benzimidazole, 2-(6-Fluoro-3-Pyridinyl)-6-(Trifluoromethyl)- undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system is designed to meet the stringent requirements of research and development, as well as pre-clinical manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.