Description

N,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-n-(2,2,2-Trifluoroethyl)Pyridin-2-Amine is a high-value, organoboron building block featuring a pinacol boronate ester group and a trifluoroethyl-substituted amine. This compound matters as a critical intermediate in modern synthetic chemistry, enabling the precise construction of complex molecules through cross-coupling reactions. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used to introduce the pyridine-boronate moiety into new generation herbicides and fungicides.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and charge-transport layers.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and bioconjugates for proteomics and diagnostic assay development.
• Catalyst Ligand Development: The structural motifs present can be utilized to develop novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke, high-value compounds for client R&D pipelines.

Basic Information

Product Name	N,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-n-(2,2,2-Trifluoroethyl)Pyridin-2-Amine
CAS No.	1356363-76-2
Molecular Formula	C15H22BF3N2O2
Molecular Weight	330.16 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,3-dimethyl-N-(2,2,2-trifluoroethyl)pyridin-2-amine; 2-Amino-N,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(2,2,2-trifluoroethyl)pyridine; N-Methyl-N-(2,2,2-trifluoroethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylpyridin-2-amine; Boronic acid, B-[2-[(methyl)(2,2,2-trifluoroethyl)amino]-6-methyl-3-pyridinyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our N,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-n-(2,2,2-Trifluoroethyl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, it is recommended to keep the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.