Description

Methyl 1-Benzyl-5,5-Difluoropiperidine-3-Carboxylate CAS NO 1356338-67-4 is a high-purity, fluorinated piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique difluorinated structure, which imparts desirable metabolic stability and lipophilicity to target molecules. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, where the difluorinated moiety can enhance biological activity and environmental persistence.
• Chemical Biology Probe Development: Serves as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal complexes.
• Fluorine Chemistry Research: An important compound for academic and industrial research focused on incorporating fluorine atoms into complex molecules.
• Fine Chemical Production: Acts as a precursor in multi-step syntheses for high-value, low-volume specialty chemicals.

Basic Information

Product Name	Methyl 1-Benzyl-5,5-Difluoropiperidine-3-Carboxylate
CAS No.	1356338-67-4
Molecular Formula	C14H17F2NO2
Molecular Weight	269.29 g/mol
Synonyms	1-Benzyl-5,5-difluoropiperidine-3-carboxylic acid methyl ester; Methyl 1-benzyl-5,5-difluoropiperidine-3-carboxylate; 3-Piperidinecarboxylic acid, 1-(phenylmethyl)-5,5-difluoro-, methyl ester; 1-Benzyl-5,5-difluoro-3-piperidinecarboxylic acid methyl ester; Methyl 1-(phenylmethyl)-5,5-difluoropiperidine-3-carboxylate; 1356338-67-4; 1-Bn-5,5-difluoropiperidine-3-COOMe
EINECS	Contact for details

Quality Control

Our Methyl 1-Benzyl-5,5-Difluoropiperidine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.