Description

5-Nitro-3-(Pyridin-3-Yl)-1H-Indazole is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological pathways and protein functions.
• Agrochemical Research: Potential application as an intermediate in the research and development of new crop protection agents.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental chemical research and custom synthesis.

Basic Information

Product Name	5-Nitro-3-(Pyridin-3-Yl)-1H-Indazole
CAS No.	1356087-84-7
Molecular Formula	C₁₂H₈N₄O₂
Molecular Weight	240.22 g/mol
Synonyms	3-(3-Pyridinyl)-5-nitro-1H-indazole; 5-Nitro-3-(3-pyridinyl)-1H-indazole; 1H-Indazole, 5-nitro-3-(3-pyridinyl)-; 5-Nitro-3-pyridin-3-yl-1H-indazole; 3-Pyridin-3-yl-5-nitro-1H-indazole; 5-Nitro-3-(3-pyridyl)-1H-indazole
EINECS	Contact for details

Quality Control

Every batch of 5-Nitro-3-(Pyridin-3-Yl)-1H-Indazole is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development applications, with specifications aligned with industry standards for advanced intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.