Description

tert-Butyl 3-Ethyl-1-Oxo-2,8-Diazaspiro[4.5]Decane-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the diazaspirocyclic chemical class. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures with potential biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing and screening compound libraries in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential component in the linker or ligand design for targeted protein degradation therapeutics.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying enzyme function and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for synthetic methodology development and bioactivity studies.

Basic Information

Product Name	tert-Butyl 3-Ethyl-1-Oxo-2,8-Diazaspiro[4.5]Decane-8-Carboxylate
CAS No.	1356086-98-0
Molecular Formula	C15H26N2O3
Molecular Weight	282.38 g/mol
Synonyms	8-Boc-3-ethyl-2,8-diazaspiro[4.5]decan-1-one; tert-Butyl 3-ethyl-1-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate; 2,8-Diazaspiro[4.5]decan-1-one, 3-ethyl-, 8-(1,1-dimethylethyl) ester; 3-Ethyl-1-oxo-2,8-diazaspiro[4.5]decane-8-carboxylic acid tert-butyl ester; Boc-3-ethyl-2,8-diazaspiro[4.5]decan-1-one; 1356086-98-0
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Ethyl-1-Oxo-2,8-Diazaspiro[4.5]Decane-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.