Description

(2S,3R,4E)-2-Amino-3-Hydroxy-Tetradecenoic Acid Ethyl Ester is a high-purity, chiral amino acid derivative with a defined stereochemistry and an unsaturated side chain. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile chiral building block for complex organic synthesis. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutics, and in fine chemical production.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of sphingolipid analogs, antimicrobial agents, and other bioactive molecules.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to sphingolipid metabolism and signaling pathways.
• Medicinal Chemistry: Serves as a core building block for structure-activity relationship (SAR) studies and drug candidate optimization.
• Fine Chemical Synthesis: Employed in the asymmetric synthesis of complex natural products and specialty chemicals requiring high stereochemical purity.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(2S,3R,4E)-2-Amino-3-Hydroxy-Tetradecenoic Acid Ethyl Ester
CAS No.	1356010-95-1
Molecular Formula	C₁₆H₃₁NO₃
Molecular Weight	285.43 g/mol
Synonyms	Ethyl (2S,3R,4E)-2-Amino-3-hydroxytetradec-4-enoate; (2S,3R,4E)-2-Azaniumyl-3-hydroxy-4-tetradecenoate Ethyl Ester; 2-Amino-3-hydroxy-4-tetradecenoic Acid Ethyl Ester (stereospecific); Sphingosine Ethyl Ester Analog; Fingolimod Intermediate; FTY720 Intermediate; Amino Hydroxy Tetradecenoate Ethyl Ester
EINECS	Contact for details

Quality Control

Our (2S,3R,4E)-2-Amino-3-Hydroxy-Tetradecenoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral assay, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) with full traceability are provided to ensure compliance with your research and cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.