Description

Methyl 3-(3-Aminophenyl)-5-Fluorobenzoate, Hcl is a high-purity organic intermediate featuring a fluorinated aromatic core and a primary amine group. This compound is critical for the synthesis of advanced pharmaceutical agents and agrochemicals, where its specific molecular architecture enables precise chemical modifications. It is primarily sought by research and development teams, as well as process chemists, in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where fluorinated aromatic structures are required.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	Methyl 3-(3-Aminophenyl)-5-Fluorobenzoate, Hcl
CAS No.	1355247-48-1
Molecular Formula	C14H13FNO2 • HCl
Molecular Weight	281.72 g/mol (Free base: 245.26 g/mol)
Synonyms	Methyl 3-Amino-5-fluorobiphenyl-3'-carboxylate hydrochloride; 3'-Carbomethoxy-5-fluoro-3-aminobiphenyl hydrochloride; 5-Fluoro-3'-(methoxycarbonyl)-[1,1'-biphenyl]-3-amine hydrochloride; Benzoic acid, 5-fluoro-3-(3-aminophenyl)-, methyl ester, hydrochloride; Methyl 5-fluoro-[1,1'-biphenyl]-3-carboxylate-3'-amine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-(3-Aminophenyl)-5-Fluorobenzoate, Hcl is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.