Description

Ethyl 4-(4-Aminophenyl)-2-Fluorobenzoate, Hcl is a high-purity, fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino group and a fluorinated benzoate ester, makes it a versatile intermediate for constructing complex pharmacophores. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorinated aromatic components in electronic display and lighting materials.
• Polymer Modification: Incorporated as a functional monomer to create specialty polymers with unique thermal, optical, or surface properties.
• Chemical Biology & Proteomics: Utilized as a scaffold or linker for developing molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	Ethyl 4-(4-Aminophenyl)-2-Fluorobenzoate, Hcl
CAS No.	1355246-93-3
Molecular Formula	C15H15FNO2·HCl
Molecular Weight	295.75 g/mol (Free base: 259.29 g/mol)
Synonyms	Ethyl 2-Fluoro-4'-(aminophenyl)-4-benzoate Hydrochloride; 4-(4-Aminophenyl)-2-Fluorobenzoic Acid Ethyl Ester Hydrochloride; Ethyl 4-Amino[1,1'-biphenyl]-3-carboxylate, 2'-Fluoro-, Hydrochloride; 2-Fluoro-4'-(aminophenyl)-4-benzoic Acid Ethyl Ester HCl; Benzoic acid, 4-(4-aminophenyl)-2-fluoro-, ethyl ester, hydrochloride; 1355246-93-3; Biphenyl derivative intermediate
EINECS	Contact for details

Quality Control

Our production of Ethyl 4-(4-Aminophenyl)-2-Fluorobenzoate, Hcl adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to support cGMP and ISO standards for reliable sourcing in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if opened for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.