Description

2-Chloro-5-Iodo-Thiazolo[5,4-B]Pyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. Pharmaceutical researchers, agrochemical developers, and material scientists need this specialized intermediate for its unique halogenated thiazolopyridine scaffold, which enables precise structural modifications to fine-tune biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its heterocyclic core for targeted biological activity.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient structure.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and enzyme functions.
• Ligand and Catalyst Development: Utilized to create novel ligands for transition metal catalysis and organocatalysts for asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized halogenated heterocycles.

Basic Information

Product Name	2-Chloro-5-Iodo-Thiazolo[5,4-B]Pyridine
CAS No.	1355241-54-1
Molecular Formula	C6H2ClIN2S
Molecular Weight	296.52 g/mol
Synonyms	2-Chloro-5-iodothiazolo[5,4-b]pyridine; Thiazolo[5,4-b]pyridine, 2-chloro-5-iodo-; 5-Iodo-2-chlorothiazolo[5,4-b]pyridine; 2-Chloro-5-iodo-[1,3]thiazolo[5,4-b]pyridine; CAS 1355241-54-1
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Iodo-Thiazolo[5,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.