Description

5-Bromo-2-Chloro-Thiazolo[5,4-B]Pyridine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the creation of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogenated thiazolopyridine motifs into their target molecules.

Application

• As a critical pharmaceutical intermediate in the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Utilized in agrochemical research for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Used in material science for constructing organic electronic materials and ligands for catalytic systems.
• Acts as a precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) in custom synthesis.

Basic Information

Product Name	5-Bromo-2-Chloro-Thiazolo[5,4-B]Pyridine
CAS No.	1355241-50-7
Molecular Formula	C6H2BrClN2S
Molecular Weight	249.51 g/mol
Synonyms	5-Bromo-2-chloro[1,3]thiazolo[5,4-b]pyridine; 2-Chloro-5-bromothiazolo[5,4-b]pyridine; Thiazolo[5,4-b]pyridine, 5-bromo-2-chloro-; 1355241-50-7; 5-Bromo-2-chlorothiazolo[5,4-b]pyridine; 2-Chloro-5-bromo-thiazolo[5,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-Thiazolo[5,4-B]Pyridine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.