Description

6-(4-Acetylpiperazin-1-Yl)-5-Methylnicotinaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a strategically functionalized nicotinaldehyde core. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by R&D and process development teams in the pharmaceutical and biotechnology industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening (HTS) against novel biological targets.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical market.

Basic Information

Product Name	6-(4-Acetylpiperazin-1-Yl)-5-Methylnicotinaldehyde
CAS No.	1355236-53-1
Molecular Formula	C14H17N3O2
Molecular Weight	259.31 g/mol
Synonyms	5-Methyl-6-(4-acetyl-1-piperazinyl)-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 6-(4-acetyl-1-piperazinyl)-5-methyl-; 6-(4-Acetylpiperazin-1-yl)-5-methylpyridine-3-carbaldehyde; 5-Methyl-6-(4-acetylpiperazin-1-yl)nicotinaldehyde; 6-(4-Acetyl-1-piperazinyl)-5-methyl-3-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 6-(4-Acetylpiperazin-1-Yl)-5-Methylnicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.