Description

6-(4-Acetylpiperazin-1-Yl)Nicotinaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a versatile bifunctional structure. This compound is critical for medicinal chemists in the research and development of novel therapeutic agents, particularly as a key building block for kinase inhibitors and other targeted small molecule drugs. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, biotechnology, and fine chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Used in the development of molecular probes to study enzyme function and cellular signaling pathways.
• Custom Synthesis: Employed by fine chemical manufacturers for the contract synthesis of specialized APIs (Active Pharmaceutical Ingredients) and novel compounds.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	6-(4-Acetylpiperazin-1-Yl)Nicotinaldehyde
CAS No.	1355229-87-6
Molecular Formula	C12H15N3O2
Molecular Weight	233.27 g/mol
Synonyms	6-(4-Acetyl-1-piperazinyl)-3-pyridinecarboxaldehyde; 6-(4-Acetylpiperazin-1-yl)pyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 6-(4-acetyl-1-piperazinyl)-; 6-(4-Acetylpiperazinyl)nicotinaldehyde; 1355229-87-6; 6-(N-Acetylpiperazino)nicotinaldehyde; 6-(4-Acetyl-piperazin-1-yl)-nicotinaldehyde
EINECS	Contact for details

Quality Control

Every batch of 6-(4-Acetylpiperazin-1-Yl)Nicotinaldehyde is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.