Description

5-Chloro-2-Fluoro-4-Methyl-Benzoic Acid Methyl Ester is a high-purity fluorinated benzoate ester, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its precise molecular architecture, which enables the efficient construction of complex molecules for demanding applications. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine and chlorine substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a protected carboxylic acid derivative in multi-step synthetic routes.
• Chemical Research & Development: Essential for academic and industrial R&D exploring new fluorinated compounds and their properties.

Basic Information

Product Name	5-Chloro-2-Fluoro-4-Methyl-Benzoic Acid Methyl Ester
CAS No.	1355070-62-0
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	Methyl 5-Chloro-2-Fluoro-4-Methylbenzoate; 5-Chloro-2-Fluoro-4-Methyl Methyl Benzoate; 2-Fluoro-5-Chloro-4-Methylbenzoic Acid Methyl Ester; Benzoic Acid, 5-Chloro-2-Fluoro-4-Methyl-, Methyl Ester; 1355070-62-0; 4-Methyl-5-Chloro-2-Fluorobenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-4-Methyl-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.