Description

5-Chloro-6-Isopropoxypyridin-3-Ol is a high-purity pyridine derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its functionalized structure, which serves as a versatile building block for constructing complex molecules with specific biological activities. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for creating functionalized ligands and complexing agents used in catalysis and advanced polymer materials.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging reagent in the development of molecular probes and tool compounds for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D programs.

Basic Information

Product Name	5-Chloro-6-Isopropoxypyridin-3-Ol
CAS No.	1355066-41-9
Molecular Formula	C8H10ClNO2
Molecular Weight	187.62 g/mol
Synonyms	5-Chloro-6-isopropoxy-3-pyridinol; 3-Pyridinol, 5-chloro-6-(1-methylethoxy)-; 5-Chloro-6-(propan-2-yloxy)pyridin-3-ol; 5-Chloro-6-isopropoxy-3-hydroxypyridine; 5-Chloro-6-(1-methylethoxy)-3-pyridinol; 1355066-41-9
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-6-Isopropoxypyridin-3-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.