Description

2-[4-(4-Fluorophenoxy)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, active ingredient synthesis, and the development of functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing biaryl structures common in many drug molecules.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorophenoxy moiety is a valuable structural component.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other advanced catalytic processes.
• Chemical Biology & Probe Synthesis: Useful for creating molecular probes and tags for biological imaging and target identification due to its borylation handle.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CROs (Contract Research Organizations) serving the global life sciences industry.

Basic Information

Item	Details
Product Name	2-[4-(4-Fluorophenoxy)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1355052-34-4
Molecular Formula	C18H20BFO3
Molecular Weight	314.16 g/mol
Synonyms	4-(4-Fluorophenoxy)phenylboronic acid pinacol ester; [4-(4-Fluorophenoxy)phenyl]boronic acid pinacol ester; 4-(4-Fluorophenoxy)benzeneboronic acid pinacol ester; 4-Fluorophenoxyphenylboronic acid pinacol ester; 4-(p-Fluorophenoxy)phenylboronic acid pinacol ester; (4-(4-Fluorophenoxy)phenyl)boronic acid pinacol ester; PINACOL 4-(4-FLUOROPHENOXY)BENZENEBORONATE
EINECS	Contact for details

Quality Control

Our 2-[4-(4-Fluorophenoxy)Phenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 19F, 11B), and GC/MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP development and research under ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged manipulations to maintain purity and stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.