Description

2-(2-Methylmorpholin-4-Yl)Pyridine-4-Carboxylic Acid Hydrochloride is a high-purity organic salt compound that serves as a critical building block in advanced pharmaceutical synthesis. This compound is valued for its role as a sophisticated intermediate in the development of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the creation of novel active pharmaceutical ingredients (APIs) and complex small molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs, leveraging its unique morpholine-pyridine scaffold.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Chemical Biology Probes: Serves as a building block for creating specialized molecular probes used to study biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	2-(2-Methylmorpholin-4-Yl)Pyridine-4-Carboxylic Acid Hydrochloride
CAS No.	1354958-10-3
Molecular Formula	C12H17ClN2O3
Molecular Weight	272.73 g/mol
Synonyms	4-Pyridinecarboxylic acid, 2-(2-methyl-4-morpholinyl)-, hydrochloride (1:1); 2-(2-Methylmorpholino)isonicotinic acid hydrochloride; 2-(2-Methyl-4-morpholinyl)isonicotinic acid hydrochloride; 2-(2-Methylmorpholin-4-yl)pyridine-4-carboxylic acid HCl; 2-(2-Methylmorpholino)pyridine-4-carboxylic acid hydrochloride; 1354958-10-3; UNII-9J6I9Q2F0P
EINECS	Contact for details

Quality Control

Our 2-(2-Methylmorpholin-4-Yl)Pyridine-4-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support development and commercial projects requiring compliance with ICH guidelines and can supply material suitable for use under cGMP conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.